On Windows, you must run the Informatica services and the Developer tool on the 64-bit platform. You can run the PowerCenter Client on a 32-bit or 64-bit platform.
A 64-bit architecture provides larger memory space that can improve caching and data throughput performance of the Integration Services. The Informatica 64-bit platform addresses up to 18 million terabytes (2^64 bytes) of system memory and has up to 256 terabytes (2^48 bytes) available for a single application.
When you run Informatica on 64-bit platforms, configure the environment to use the correct libraries, database clients, and session cache sizes.
Use the following guidelines when you install Informatica services on 64-bit Windows:
Link 64-bit applications with 64-bit libraries.
Link 64-bit machines where the Data Integration Service, PowerCenter Repository Service, or PowerCenter Integration Service runs with a 64-bit database client.